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  • ChemNote: Thallium Poisoning ChemSee

    The toxicity of thallium is mainly due to the fact that the mono-valent thallium ion Tl +1 has many properties which are very similar to the common ions potassium, K +1 and sodium Na +1. Since the size of the thallium ion is very close to that of the potassium ion, certain biochemical mechanisms in the body cannot distinguish between the two ...

  • Thallium poisoning - Wikipedia

    Thallium poisoning is poisoning due to thallium and its compounds which are often highly toxic. Contact with skin is dangerous, and adequate ventilation should be provided when melting this metal. Many thallium(I) compounds are highly soluble in water and are readily absorbed through the skin. [citation needed] Exposure to them should not exceed 0.1 mg per m 2 of skin in an 8-hour time ...

  • Specialty: Toxicology
  • Thallium: What Are the Symptoms of Poisoning?

    Thallium itself and compounds containing the element are highly toxic. It is particularly dangerous because compounds containing thallium are colorless, odorless, and tasteless. Because of this high toxicity, the World Health Organization (WHO) recommends against the use of thallium in rodent and insect poisons. However, poisons containing ...

  • THALLIUM : Systemic Agent - CDC

    May 12, 2011  Urine thallium levels above 5 µg/L are abnormal, with levels above 200 µg/L being indicative of poisoning. Thallium blood concentration levels are normal below 2 µg/L, and toxic at concentrations greater than 200 µg/L. DELAYED EFFECTS OF EXPOSURE: Long-term effects of thallium exposure can include difficulty walking, various involuntary ...

  • Thallium Detection ChemSee

    About Thallium Toxicity Thallium and its compounds are often highly toxic. Contact with skin is dangerous, and adequate ventilation should be provided when melting this metal. Many thallium(I) compounds are highly soluble in water and are readily absorbed through the skin.[citation needed] Exposure to them should not exceed 0.1 mg per m2 of skin...

  • ChemNote: Arsenic Poisoning ChemSee

    ChemNote: Arsenic Poisoning Why Arsenic and its Compounds Can poison Quickly, (Acutely), as Well as Over a Long Term, (Chronically), and Why They are Used Often by Poisoners and Terrorists? The effects of poisoning with Arsenic may be apparent in short time or only after a prolonged exposure.

  • Mercury Detection ChemSee

    About Mercury Toxicity Common symptoms of mercury poisoning include peripheral neuropathy (presenting as paresthesia or itching, burning or pain), skin discoloration (pink cheeks, fingertips and toes), swelling, and desquamation (shedding or peeling of skin). Mercury irreversibly inhibits selenium-dependent enzymes (see below) and may also inactivate S-adenosyl-methionine, which is necessary ...

  • ChemNote: Azides ChemSee

    Azides Uses, Properties, Toxicity and Safety, Detection and Safe Decontamination and Destruction. A. General Description Azides are compounds which contain three nitrogen atoms connected to each other, -N3, where the letter N denotes an atom of the element nitrogen. The subscript 3 signifies that three nitrogen atoms are bonded to each other. The free arm...

  • Thallium Poisoning: Symptoms, Diagnosis and Treatment ...

    Thallium poisoning causes symptoms within hours after ingestion. Initial complaints are related to the gastrointestinal system and include abdominal pain, nausea, vomiting, hematemesis and diarrhea which often contains blood [12]. At this stage, symptoms are nonspecific and

  • Clinical characteristics and treatment of thallium ...

    poisoning. We conducted a retrospective descriptive analysis of patients in our hospital from 2008 to 2018 who had thallium poisoning and experienced a delay in hospital admission. The time from symptom onset to admission was assessed. The patients were divided into 3 groups and descriptive analyses of their clinical characteristics, including basic patient information, symptoms, laboratory ...

  • Thallium poisoning. Diagnosis may be elusive but alopecia ...

    Jun 05, 1993  The elimination half time of thallium is between 1.7 and 30 days depending on the time since, and chronicity of, ingestion. The elimination time phases are apparent and because of the long terminal elimination half time thallium may act as a cumulative poison. We present two cases of thallium poisoning with intent to kill.

  • Thallium poisoning Symptoms, Diagnosis, Treatments and ...

    Thallium poisoning: Introduction. Thallium poisoning: The poisoning of a person with the element thallium. More detailed information about the symptoms, causes, and treatments of Thallium poisoning is available below.. Symptoms of Thallium poisoning

  • Thallium Poisoning. What is thallium poisoning? Symptoms ...

    Jun 23, 2015  Thallium poisoning usually follows oral ingestion but it can be inhaled from contaminated dust from pyrite burners, cadmium manufacturing, lead and zinc smelting and in contamination of heroin or cocaine. Its toxic effect is due to its ability to inhibit a number of intracellular potassium-mediated processes. It is used in the manufacture of ...

  • Chemist found guilty of murder News Chemistry World

    It was not until several days later that thallium poisoning was suspected and a urine sample sent for testing. To do that the sample had to be transferred to a lab in another state. The actual test for thallium is quite simple, says Barry Samson, director of the trace element laboratory at Charing Cross Hospital in London, UK, explaining that ...

  • Thallium Poisoning - an overview ScienceDirect Topics

    Robyn Blain, George Kazantzis, in Handbook on the Toxicology of Metals (Fourth Edition), 2015. 8 Diagnosis, Treatment, and Preventive Measures. The diagnosis of thallium poisoning may be difficult because it is often unsuspected. The cardinal features are gastroenteritis, peripheral neuropathy, and, later, alopecia, with the latter occurring at a stage when treatment is likely to be ineffective.

  • A 15-year-old case yields a timely clue in deadly thallium ...

    Mar 31, 2019  Although committed to an institution for the criminally insane, Young was released in 1971 and promptly killed two co-workers and seriously injured two more — all with thallium poisoning.

  • Symptoms of Thallium poisoning - RightDiagnosis

    Thallium poisoning as a Cause of Symptoms or Medical Conditions. When considering symptoms of Thallium poisoning, it is also important to consider Thallium poisoning as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Thallium poisoning may cause: Abdominal pain; Anagen effluvium

  • Thallium poisoning: a review.

    Thallium poisoning: a review. Saddique A, Peterson CD. Thallium poisoning is one of the most complex and serious toxicities known to man. The symptomatology of its toxicity is usually nonspecific due to the multi-organ involvement. The initial symptoms of thallium poisoning may include fever, gastrointestinal problems, delirium, convulsions and ...

  • Thallium - Wikipedia

    Thallium is a chemical element with the symbol Tl and atomic number 81. It is a gray post-transition metal that is not found free in nature. When isolated, thallium resembles tin, but discolors when exposed to air.Chemists William Crookes and Claude-Auguste Lamy discovered thallium independently in 1861, in residues of sulfuric acid production. Both used the newly developed method of flame ...

  • Facts About Thallium Poisoning on MedicineNet

    Thallium can be absorbed from the skin as well as be ingested or inhaled. If a significant amount (significant poisoning is usually defined as ingesting over 1 gram of thallium, or over 8 milligrams per kilogram of body weight) of thallium enters the body, symptoms of thallium poisoning develop. In the first 48 hours after serious thallium ...

  • Thallium Poisoning California Poison Control System (CPCS)

    Sep 23, 2007  Thallium poisoning should be suspected in any patient with neurological symptoms and hair loss. Gastrointestinal findings may be mild or nonexistent, especially in chronic poisoning. Thallium blood levels may be elevated after recent exposures, but it is cleared from the blood relatively quickly. Cases of known thallium exposure may be ...

  • Thallium poisoning: a review.

    Thallium poisoning: a review. Saddique A, Peterson CD. Thallium poisoning is one of the most complex and serious toxicities known to man. The symptomatology of its toxicity is usually nonspecific due to the multi-organ involvement. The initial symptoms of thallium poisoning may include fever, gastrointestinal problems, delirium, convulsions and ...

  • Thallium - Wikipedia

    Thallium is a chemical element with the symbol Tl and atomic number 81. It is a gray post-transition metal that is not found free in nature. When isolated, thallium resembles tin, but discolors when exposed to air.Chemists William Crookes and Claude-Auguste Lamy discovered thallium independently in 1861, in residues of sulfuric acid production. Both used the newly developed method of flame ...

  • Facts About Thallium Poisoning on MedicineNet

    Thallium can be absorbed from the skin as well as be ingested or inhaled. If a significant amount (significant poisoning is usually defined as ingesting over 1 gram of thallium, or over 8 milligrams per kilogram of body weight) of thallium enters the body, symptoms of thallium poisoning develop. In the first 48 hours after serious thallium ...

  • Thallium Poisoning California Poison Control System (CPCS)

    Sep 23, 2007  Thallium poisoning should be suspected in any patient with neurological symptoms and hair loss. Gastrointestinal findings may be mild or nonexistent, especially in chronic poisoning. Thallium blood levels may be elevated after recent exposures, but it is cleared from the blood relatively quickly. Cases of known thallium exposure may be ...

  • ATSDR - Toxicological Profile: Thallium

    Sep 26, 2019  The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies.

  • Thallium poisoning: an outbreak in Florida, 1988.

    In October 1988, five of seven members of a Florida family were poisoned with thallium, constituting the largest outbreak of acute thallium poisoning in the United States since thallium was banned as a rodenticide in 1972. Three patients had an acute severe neuropathy with respiratory depression; one died. The other two had no symptoms.

  • Presence of thallium in the environment: sources of ...

    Oct 26, 2016  The toxicity of thallium-based compounds is mainly caused by the similarity between thallium (I) ions and potassium ions (Groesslova et al. 2015), which results in the disorder of potassium-associated metabolic processes due to thallium interference (Sager 1998; Wojtkowiak et al. 2016). Human exposure to thallium is mainly associated with the ...

  • The Chemistry of Poisons – Thallium, ‘The Poisoner’s ...

    Mar 19, 2015  The toxicity of thallium and its compounds was quickly noticed; experiments in which the compound was fed to animals saw all of the test subjects die within a few days. Despite its toxicity, thallium compounds saw use in medicinal treatment of a number of conditions. Thallium sulfate was used for the treatment of diseases and conditions ...

  • Thallium Toxicity - Medscape

    History. The clinical presentation of thallium toxicity can vary depending on the type, severity, and timeframe of the exposure. Acute thallium poisoning is primarily characterized by gastrointestinal, neurological, and dermatological symptoms, while neurologic findings predominate with chronic exposure and tend to progress, even despite decreasing blood thallium levels.

  • Thallium: a review of public health and environmental ...

    Thallium (Tl) is a rare but widely dispersed element. All forms of thallium are soluble enough to be toxic to living organisms. Thallium is more toxic to humans than mercury, cadmium, lead, copper or zinc and has been responsible for many accidental, occupational, deliberate, and therapeutic poisonings since its discovery in 1861.

  • Thallium exists in opioid poisoned patients

    Aug 01, 2015  Thallium (Tl) is a toxic heavy metal that exists in nature. Tl poisoning (thallotoxicosis) may occur in opioid addicts. This study was designed to evaluate the frequency and level of urinary Tl in opioid abusers. In addition, clinical findings were evaluated.

  • Thallium in the human body - Lead Poisoning - Flanders ...

    May 22, 2020  A case of misdiagnosed poisoning with thallium sulphate was reported in 1977, but the victim was saved thanks to Christie's The Pale Horse. A 19-month-old girl living in Qatar had been taken very ill and the doctors there had been unable to diagnose the cause of her illness, so her parents took her to London for specialist treatment.

  • The Chemist as Murderer (A Thallium Story) WIRED

    The cause was eventually found to be poisoning by the toxic element thallium. The victim survived after receiving a life-saving antidote although she suffered lingering disabilities from the attack.

  • ATSDR - Public Health Statement: Thallium

    Jan 21, 2015  Pure thallium is a soft, bluish�white metal that is widely distributed in trace amounts in the earth's crust. In its pure form, it is odorless and tasteless. It can be found in pure form or mixed with other metals in the form of alloys. It can also be found combined with other substances such as bromine, chlorine, fluorine, and iodine to form salts.

  • Thallium exists in opioid poisoned patients

    Aug 01, 2015  Thallium (Tl) is a toxic heavy metal that exists in nature. Tl poisoning (thallotoxicosis) may occur in opioid addicts. This study was designed to evaluate the frequency and level of urinary Tl in opioid abusers. In addition, clinical findings were evaluated.

  • Thallium in the human body - Lead Poisoning - Flanders ...

    May 22, 2020  A case of misdiagnosed poisoning with thallium sulphate was reported in 1977, but the victim was saved thanks to Christie's The Pale Horse. A 19-month-old girl living in Qatar had been taken very ill and the doctors there had been unable to diagnose the cause of her illness, so her parents took her to London for specialist treatment.

  • The Chemist as Murderer (A Thallium Story) WIRED

    The cause was eventually found to be poisoning by the toxic element thallium. The victim survived after receiving a life-saving antidote although she suffered lingering disabilities from the attack.

  • ATSDR - Public Health Statement: Thallium

    Jan 21, 2015  Pure thallium is a soft, bluish�white metal that is widely distributed in trace amounts in the earth's crust. In its pure form, it is odorless and tasteless. It can be found in pure form or mixed with other metals in the form of alloys. It can also be found combined with other substances such as bromine, chlorine, fluorine, and iodine to form salts.

  • What is Thallium Poisoning? (with pictures)

    Thallium (Tl) is a silver-colored, soft, metallic element found in trace quantities with several other metals, and is usually recovered as a byproduct from smelting lead, copper and zinc.The minute amount of the chemical which occurs naturally in water is relatively harmless, but thallium is highly toxic in larger quantities, and as little as 0.3 ounces (1 gram) can be fatal in humans.

  • Thallium poisoning: emphasis on early diagnosis and ...

    Thallium poisoning is known for its diverse manifestations and these can delay the diagnosis if a clear history of poisoning is not forthcoming. A 42 year old man presented on the third day of illness with flaccid quadriparesis and paresthesia, which were confused with Guillain-Barré syndrome. Because of associated loose motions, skin lesions, and liver and kidney dysfunction arsenic ...

  • What is thallium — and can it kill you? - The Morning Call

    Dec 20, 2018  Thallium has its place in noir fiction (Agatha Christie’s “The Pale Horse”) and nightly news headlines (most recently the suspected poisoning of former Russian security agent Alexander ...

  • Thallium poisoning DermNet NZ

    Thallium poisoning is via ingestion or absorption through the skin. The lethal dose for humans is 15-20 mg/kg, although much small doses have also led to death. Non-lethal doses cause toxic effects. Prolonged exposure may lead to build-up and chronic poisoning.

  • Thallium Toxicity: Practice Essentials, Background ...

    Feb 19, 2018  Acute thallium poisoning is primarily characterized by gastrointestinal, neurological, and dermatological symptoms, while neurologic findings predominate with chronic exposure and tend to progress, even despite decreasing blood thallium levels. [6, 7] (See Presentation.)

  • Toxicological Review of Thallium and compounds (CAS No ...

    Thallium toxicity in animals via injection ..... 366 Table 5-1. Incidence data and BMD modeling results for selected clinical observations in Sprague-Dawley rats treated with thallium sulfate for 90 days ..... 61 . Table B-1. A summary of BMDS (version 1.4.1) modeling results based on incidence of ...

  • Thallium poisoning. Diagnosis may be elusive but alopecia ...

    Thallium is a heavy metal whose salts are used in some rodent poisons and in the manufacture of optical lenses, semiconductors, scintillation counters, low temperature thermometers, and switching devices, green coloured fireworks, and imitation jewelery, and as chemical catalysts. In clinical practice thallium isotopes are used in cardiac scanning, but the use of thallium salts to treat scalp ...

  • Everyday Uses of Thallium You Didn’t Know About

    Sep 17, 2018  Thallium Poisoning Symptoms. Thallium poisoning foments adverse effects on the nervous system and may cause vomiting, diarrhea, temporary hair loss, and impediments to the lungs, heart, liver, and kidneys. In some instances, thallium poisoning leads to death. Thallium is readily absorbed through the skin, respiration, and the digestive tract.

  • Week 7 - 8 Inorganic Poisons - Thallium - Toxicology ...

    It was suggested, in fact it was suggested by Graham Young himself, that this looked like a thallium poisoning. So, the investigators went back and re-investigated Bob Egle's death. Now, remember, he's been cremated, but we're talking about thallium. Thallium is an element, so thallium

  • Thallium Toxicity - Chelation Medical Center LLC

    Thallium Toxicity Thallium (Tl) Thallium can be assimilated transdermal (through the skin), by inhalation, or by oral ingestion. Both valence states can have harmful effects: Thallium+1 may displace potassium from binding sites and influences enzyme activities;